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Hayden Panettiere died from an accidental overdose involving fentanyl, coroner’s office says

Hayden Panettiere appears at an event on January 5, 2017, in New York City.
Roy Rochlin/FilmMagic/Getty Images/File via CNN Newsource
Hayden Panettiere appears at an event on January 5, 2017, in New York City.

Originally Published: 22 SEP 26 10:18 ET

Updated: 22 SEP 26 11:59 ET

By Holly Yan, CNN

(CNN) — Actress Hayden Panettiere died from the toxic effects of fentanyl and other substances, and her death has been ruled an accident, the Greenville County Coroner’s Office in South Carolina said Tuesday.

Panettiere, who starred in the TV shows “Heroes” and “Nashville,” was pronounced dead at a Greenville apartment on August 16. Medics responding to a 911 call found the 36-year-old in cardiac arrest and were unable to resuscitate her.

The coroner’s office ruled the cause of death as the “toxic effects of fentanyl, 4-ANPP, Alprazolam, Methocarbamol, and Quetiapine.”

Fentanyl and other synthetic opioids are involved in more than half of all overdose deaths in the United States, according to data from the US Centers for Disease Control and Prevention.

While overdose deaths have dropped significantly over the past few years, the most recent provisional data suggest fentanyl and other synthetic opioids were involved in more than 35,000 US deaths in the past year.

Despite concluding the actor’s death was accidental, authorities continue investigating whether anyone might be criminally responsible for providing her with a lethal substance.

Drug Enforcement Administration agents and Los Angeles-area authorities have questioned several people about the circumstances surrounding the California resident’s death, a source familiar with the case said last week.

Investigators were looking into whether Panettiere may have taken a counterfeit narcotic and whether it may have interacted with any other substances in her body at the time of her death, the source added.

“The investigation remains ongoing and the circumstances surrounding the case are complex,” Panettiere’s representative, Kasey Kitchen, said in a statement to CNN shortly after the coroner’s report. “We must all continue to remain patient and allow the investigative process to unfold.”

The actress had spoken publicly about her battles with mental health and substance abuse. Postpartum depression and addiction plagued her young adult years and temporarily halted the career that began when she was less than a year old.

But this year, Panettiere addressed her struggles in a memoir and spoke publicly about losing her brother. And her career was making a comeback, with her latest film released in January.

So when the 36-year-old was pronounced dead in the South Carolina apartment building, shock and grief stretched from Hollywood to Ukraine. Panettiere’s ex-partner, former Olympic and world boxing champion Wladimir Klitschko, paid tribute to Panettiere and vowed to make sure their daughter Kaya would always remember her mother.

Panettiere “had been temporarily staying” at the apartment in Greenville, the coroner’s office said in August. Authorities did not say whose apartment it was.

Her boyfriend, Brian Hickerson, and his brother Zach called 911 the afternoon of August 16 to say Panettiere was unresponsive, according to a Greenville police incident report. The brothers were questioned separately at the scene, and Brian Hickerson gave an officer a bag of Panettiere’s medications, the report said.

The Hickersons have roots in Greenville, where some of their family members live. According to the police report, Brian Hickerson lived in California, and Zach Hickerson lived in Georgia.

Panettiere’s death – along with revelations from her recently released memoir – cast new light on the challenges of growing up in the public spotlight. Her tragic fate has inspired other former child stars to speak out about the pressure and struggles that often accompany fame at an early age.

This story has been updated with additional information.

CNN’s Josh Campbell, Deidre McPhillips, Nadia Kounang and Elizabeth Wagmeister contributed to this report.

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